WWTR1 - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | WWTR1 - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This is a rabbit polyclonal antibody against WWTR1. It was validated on Western BlotTarget Description: WWTR1 is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. It regulates the nuclear accumulation of S |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human WWTR1 |
| Other Names | [WW domain-containing transcription regulator protein 1; WW domain-containing transcription regulator protein 1; WW domain-containing transcription regulator protein 1; WW domain containing transcription regulator 1; Transcriptional coactivator with PDZ-binding motif] |
| Gene, Accession # | [WWTR1], Gene ID: 25937, NCBI: NP_056287, UniProt: Q9GZV5 |
| Catalog # | MBS3219640 |
| Price | $335 |
| Order / More Info | WWTR1 - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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