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Antigenic Specificity | LRRTM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least two isoforms of LRRTM3 are known to exist; this antibody will only detect the larger isoform. LRRTM3 Antibody: The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Recent evidence suggests that LRRTM3 promotes the processing of amyloid-precursor protein (APP) by the beta-secretase BACE, leading to the proteolytic production of the Abeta42 peptide that is the main component of amyloid plaques. Furthermore, LRRTM3 maps to a region of chromosome 10 linked to both late-onset Alzheimer |
Immunogen | Immunogen: LRRTM3 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of human LRRTM3. Buffer: LRRTM3 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [LRRTM3; Leucine-rich repeat transmembrane neuronal protein 3; leucine rich repeat transmembrane neuronal 3], [LRRTM3; LRRTM3] |
Gene, Accession # | [LRRTM3], Gene ID: 347731, NCBI: NP_821079, UniProt: Q86VH5 |
Catalog # | MBS150313 |
Price | $375 |
Order / More Info | LRRTM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |