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Antigenic Specificity | ARHGDIA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total ARHGDIA protein. Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze the exchange of bound GDP for GTP, and inhibited by GTPase activating proteins (GAPs), which catalyze the hydrolysis of GTP to GDP. A third level of regulation is provided by the stoichiometric binding of Rho GDP dissociation inhibitor (RhoGDI). RhoGDI affects Rho activity by inhibiting nucleotide exchange and membrane association, regulating activity and localization (Reviewed in 1, 2). The inhibitory and shuttling functions of |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human ARHGDIA. |
Other Names | [ARHGDIA; GDIA1; MGC117248; RHOGDI; RHOGDI-1] |
Gene, Accession # | [ARHGDIA], Gene ID: 396, NCBI: NP_001172006.1, UniProt: P52565 |
Catalog # | MBS9413899 |
Price | $255 |
Order / More Info | ARHGDIA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |