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Antigenic Specificity | GRIN2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity). |
Immunogen | Immunogen: Recombinant human Glutamate receptor ionotropic, NMDA 2B protein (1185-1484aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-31543 / sc-31545 / sc-1469 / sc-9057 |
Other Names | [GluN2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; NR2B; N-methyl-D-aspartate receptor subunit 3; NR3; hNR3; GRIN2B; NMDAR2B], [GRIN2B; GRIN2B; MRD6; NR2B; hNR3; EIEE27; GluN2B; NMDAR2B; NMDAR2B; GluN2B; NMDAR2B; NR2B; NR3; hNR3] |
Gene, Accession # | [GRIN2B], Gene ID: 2904, NCBI: NP_000825.2, UniProt: Q13224 |
Catalog # | MBS1495098 |
Price | $120, $160 |
Order / More Info | GRIN2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |