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Antigenic Specificity | PELP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1. May have important functional implications in ER/growth factor cross-talk. Interacts with several growth factor signaling components including EGFR and HRS. Involved in nuclear receptor signaling via its interaction with AR and NR3C1. May promote tumorigenesis |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1021-1180 of human PELP1 (NP 055204.3). |
Other Names | [MNAR; P160] |
Gene, Accession # | [PELP1], Gene ID: 27043, NCBI: Q8IZL8.2, UniProt: Q8IZL8 |
Catalog # | MBS8548226 |
Price | $280 |
Order / More Info | PELP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |