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Antigenic Specificity | SUZ12 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A. |
Immunogen | Immunogen: A synthesized peptide derived from human SUZ12. Subcellular Localization: Nucleus. Tissue Specificity: Overexpressed in breast and colon cancer. |
Other Names | [Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog; SUZ12; CHET9; JJAZ1; KIAA0160], [SUZ12; SUZ12; CHET9; JJAZ1; CHET9; JJAZ1; KIAA0160; ChET 9 protein] |
Gene, Accession # | [SUZ12], Gene ID: 23512, NCBI: NP_056170.2, UniProt: Q15022 |
Catalog # | MBS179378 |
Price | $160, $340, $340 |
Order / More Info | SUZ12 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |