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Antigenic Specificity | Parkinson's Research Antibody Sampler Kit |
Clone | n/a |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 1 kit |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Parkinson's disease (PD), the second most common neurodegenerative disease after Alzheimer's, is a progressive movement disorder characterized by rigidity, tremors, and postural instability. The pathological hallmark of PD is progressive loss of dopaminergic neurons in the substantia nigra of the ventral midbrain and the presence of intracellular Lewy bodies in surviving neurons of the brain stem. Research studies have shown that various genes and loci (alpha-synuclein/PARK1 and 4, parkin/PARK2, UCH-L1/PARK5, PINK1/PARK6, DJ-1/PARK7, LRRK2/PARK8, synphilin-1, and NR4A2) are genetically linked to PD. alpha-Synuclein, a 140 amino acid protein expressed abundantly in the brain, is a major component of aggregates found in Lewy bodie |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS2549985 |
Price | $295 |
Order / More Info | Parkinson's Research Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |