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Antigenic Specificity | HNMT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HNMT protein. In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human HNMT. |
Other Names | [HMT; HNMT-S1; HNMT-S2] |
Gene, Accession # | [HNMT], Gene ID: 3176, NCBI: NP_001019245.1, UniProt: P50135 |
Catalog # | MBS9402690 |
Price | $255 |
Order / More Info | HNMT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |