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Antigenic Specificity | POLD2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | As a component of the trimeric and tetrameric DNA polymerase delta complexes (Pol-delta3 and Pol-delta4, respectively), plays a role in high fidelity genome replication, including in lagging strand synthesis, and repair (PubMed:12403614, PubMed:16510448, PubMed:19074196, PubMed:20334433, PubMed:24035200). Pol-delta3 and Pol-delta4 are characterized by the absence or the presence of POLD4. They exhibit differences in catalytic activity. Most notably, Pol-delta3 shows higher proofreading activity than Pol-delta4 (PubMed:19074196, PubMed:20334433). Although both Pol-delta3 and Pol-delta4 process Okazaki fragments in vitro, Pol-delta3 may also be better suited to fulfill this task, exhibiting near-absence of strand displacement activity compare |
Immunogen | Immunogen: Recombinant Human DNA polymerase delta subunit 2 protein (245-430AA) |
Other Names | [DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; POLD2] |
Gene, Accession # | [POLD2], Gene ID: 5425, NCBI: NP_001120690.1, UniProt: P49005 |
Catalog # | MBS7108035 |
Price | $160, $235 |
Order / More Info | POLD2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |