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Antigenic Specificity | Phospho-BAD (S71) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.31 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S71 of human BAD. The protein encoded by this gene is a member of the BCL-2family. BCL-2 family members are known to be regulators ofprogrammed cell death. This protein positively regulates cellapoptosis by forming heterodimers with BCL-xL and BCL-2, andreversing their death repressor activity. Proapoptotic activity ofthis protein is regulated through its phosphorylation. Proteinkinases AKT and MAP kinase, as well as protein phosphatasecalcineurin were found to be involved in the regulation of thisprotein. Alternative splicing of this gene results in twotran |
Immunogen | n/a |
Other Names | [Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; BAD; BBC6; BCL2L8] |
Gene, Accession # | [BAD], Gene ID: 572, NCBI: NP_004313.1, UniProt: Q92934 |
Catalog # | MBS9207584 |
Price | $165, $370 |
Order / More Info | Phospho-BAD (S71) Antibody from MYBIOSOURCE INC. |
Product Specific References | Chen, B., et al. Am. J. Physiol., Cell Physiol. 299 (5), C968-C976 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Galmiche, A., et al. Mol. Cancer Res. 8(8):1116-1125(2010) Cerioni, L., et al. Methods Mol. Biol. 648, 291-301 (2010) : Yu, B., et al. J. Exp. Clin. Cancer Res. 29, 107 (2010) : |