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Antigenic Specificity | LC3C-Specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | humanpredicted: sheep |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: LC3C-Specific Antibody detects endogenous levels of LC3C-Specific. Description: Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium (PubMed:23022382). May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins (PubMed:28404643).Post Translational Modifications: The precursor molecule is cleaved by ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II (PubMed:15187094). The Legionella effector RavZ is a decon |
Immunogen | Immunogen: A synthesized peptide derived from human LC3C-Specific. Tissue Specificity: Most abundant in placenta, lung and ovary. |
Other Names | [ATG8J; Autophagy-related protein LC3 C; Autophagy-related ubiquitin-like modifier LC3 C; LC3 like protein 2; MAP1 light chain 3 like protein 2; MAP1 light chain 3 like protein 3; MAP1 light chain 3-like protein 3; MAP1A/MAP1B LC3 C; MAP1A/MAP1B light chain 3 C; MAP1LC3C; Microtubule-associated protein 1 light chain 3 gamma; Microtubule-associated proteins 1A/1B light chain 3C; MLP3C_HUMAN] |
Gene, Accession # | [LC3C], Gene ID: 440738, NCBI: NP_001004343, UniProt: Q9BXW4 |
Catalog # | MBS9611875 |
Price | $240, $280 |
Order / More Info | LC3C-Specific Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |