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Antigenic Specificity | PRMT7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 513-692 of human PRMT7 (NP 061896.1). |
Other Names | [SBIDDS] |
Gene, Accession # | [PRMT7], Gene ID: 54496, NCBI: NP_061896.1, UniProt: Q9NVM4 |
Catalog # | MBS8548149 |
Price | $280 |
Order / More Info | PRMT7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |