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Antigenic Specificity | Casp3 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, goat, guinea pig, horse, human, porcine, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against Casp3. It was validated on Western BlotTarget Description: Casp3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond, cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain, cleaves and activates caspase-6, -7 and -9, triggers cell adhesion in sympathetic neurons through RET cleavage, cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Casp3 |
Other Names | [caspase-3; Caspase-3; caspase-3; caspase 3; Apopain; Cysteine protease CPP32; CPP-32] |
Gene, Accession # | [CASP3], Gene ID: 12367, NCBI: NP_033940, UniProt: P70677 |
Catalog # | MBS3215043 |
Price | $335 |
Order / More Info | Casp3 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |