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Antigenic Specificity | DISC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0 mg/ml |
Applications | Immunohistology Frozen, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognises disrupted in schizophrenia 1 (DISC1), 93kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. . . In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.This product has been found suitable for immunocytochemistry (ICC) at a concentration of 5ug/ml. MBS222900 recognises disrupted in schizophrenia 1 (DISC1), 93k |
Immunogen | Perservative Stabilisers: 0.02% Sodium Azide. Preparation: Antisera to human DISC1 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography. |
Other Names | [disrupted in schizophrenia 1 protein isoform Lv; Disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1], [DISC1; DISC1; SCZD9; C1orf136; KIAA0457] |
Gene, Accession # | [DISC1], Gene ID: 27185, NCBI: NP_001012975.1, UniProt: Q9NRI5 |
Catalog # | MBS222900 |
Price | $375 |
Order / More Info | DISC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |