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Antigenic Specificity | VIMENTIN |
Clone | polyclonal |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Vimentin, also know as VIM. It is the major subunit protein of the intermediate filaments of mesenchymal cells. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an i |
Immunogen | Immunogen: Purified recombinant fragment of Vimentin (aa2-466) expressed in E. Coli. |
Other Names | [vimentin; Vimentin; vimentin; vimentin], [VIM; VIM] |
Gene, Accession # | [VIM], Gene ID: 7431, NCBI: NP_003371.2, UniProt: P08670 |
Catalog # | MBS850410 |
Price | $280 |
Order / More Info | VIMENTIN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |