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Antigenic Specificity | Rat GluN2B/NR2B |
Clone | [S59-36] |
Host Species | Mouse |
Reactive Species | human, rat, mouse |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | WB, IHC, ICC/IF, IP, AM |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~166kDa. No cross-reactivity against NR2A. Background Info: Detects ~166kDa. No cross-reactivity against NR2A Scientific Background: NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (1). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for anti-nociceptive drugs, and may also be useful as analgesics (2). |
Immunogen | Immunogen: Fusion protein amino acids 20-271 (extracellular N-terminus) of rat NR2B. |
Other Names | [GluN2B/NR2B, 559-36; NMDAR2B; hNR3; MGC142180; glutamate receptor subunit epsilon-2; NR3], [Grin2b; Grin2b; GluN2B; GluN2B; NMDAR2B; NR2B] |
Gene, Accession # | Gene ID: 24410, NCBI: NP_036706.1, UniProt: Q00960 |
Catalog # | MBS800075 |
Price | $390 |
Order / More Info | Rat GluN2B/NR2B Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Zhuo M. (2009) Mol Brain. 2(1): 4 4. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406. |