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Antigenic Specificity | Human CD273 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item detects human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a single-pass type 1 membrane protein belonging to the immunoglobulin receptor superfamily, and is a ligand for CD279 (PD-1). . . CD273 is highly expressed in the tissues of the heart, liver, lung, placenta and pancreas. It is expressed in dendritic cells, and its expression can be induced on inflammatory macrophages when activated by interleukin 4 or Th2 cells. . . CD273 functions to inhibit T-cell proliferation by blocking cell cycle progression and cytokine production, and is particularly important in the maintenance of self tolerance. MBS223722 detects human CD273, also known as B7-DC and Programmed Death Ligand 2 (PD-L2). CD273 is a s |
Immunogen | Immunogen: A peptide corresponding to a 16 amino acid sequence from near the centre of Human CD273. Histology Positive Control Tissue: Mouse brain tissue Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Human CD273 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [programmed cell death 1 ligand 2; Programmed cell death 1 ligand 2; programmed cell death 1 ligand 2; B7 dendritic cell molecule; B7-DC; PD-1 ligand 2; PD-1-ligand 2; PDCD1 ligand 2; butyrophilin B7-DC; programmed death ligand 2; programmed cell death 1 ligand 2; Butyrophilin B7-DC; B7-DC; CD_antigen: CD273], [PDCD1LG2; PDCD1LG2; B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2; B7DC; CD273; PDCD1L2; PDL2; PD-1 ligand 2; PD-L2; PDCD1 ligand 2; Programmed death ligand 2; B7-DC] |
Gene, Accession # | [CD273], Gene ID: 80380, NCBI: NP_079515.2, UniProt: Q9BQ51 |
Catalog # | MBS223722 |
Price | $375 |
Order / More Info | Human CD273 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |