DAPK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDAPK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: DAPK3 antibody detects endogenous levels of total DAPK3. Function: Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase-dependent) apoptotic and type II (caspase-independent) autophagic cell deaths signal, depending on the cellular setting. Involved in regulation of starvation-induced autophagy. Regulates myosin phosphorylation in both smooth muscle and non-muscle cells. In smooth muscle, regulates myosin either directly by phosphorylating MYL12B and MYL9 or through inhibition of smooth muscle myosin phosphatase (SMPP1M) via phosphorylation of P
ImmunogenImmunogen: A synthesized peptide derived from human DAPK3 Subcellular Location: Nucleus. Cytoplasm. Nucleus > PML Body. Relocates to the cytoplasm on binding PAWR where the complex appears to interact with actin filaments (By similarity). Localizes to promyelocytic leukemia protein nuclear bodies (PML-NBs). Associates to centromeres from prophase to anaphase. Tissue Specificity: Widely expressed. Isoform 1 and isoform 2 are expressed in the bladder smooth muscle. Predicted Cr
Other Names[DAP kinase 3; DAP like kinase; DAP-like kinase; Dapk 3; DAPK3; DAPK3_HUMAN; Death associated kinase 3; Death associated protein kinase 3; Death-associated protein kinase 3; Dlk; EC 2.7.11.1; FLJ36473; MYPT1 kinase; ZIP; ZIP kinase; ZIP kinase isoform; ZIP-kinase; ZIPK; zipper-interacting protein kinase]
Gene, Accession #[DAPK3], Gene ID: 1613, NCBI: NP_001339.1, UniProt: O43293
Catalog #MBS9608404
Price$240, $280
Order / More InfoDAPK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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