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Antigenic Specificity | Phospho-eIF4E (S209) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-eIF4E (S209) antibody detects endogenous levels of total Phospho-eIF4E (S209). eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. |
Immunogen | Immunogen: A synthesized peptide derived from human Phospho-eIF4E (S209) |
Other Names | [CBP; eIF-4E; eIF-4F 25 kDa subunit; EIF4F; EIF4E1; EIF4EL1; MGC111573; EIF4E] |
Gene, Accession # | [eIF4E], Gene ID: 1977, NCBI: NP_001124150.1, UniProt: P06730 |
Catalog # | MBS4750177 |
Price | $335 |
Order / More Info | Phospho-eIF4E (S209) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |