Edit |   |
---|---|
Antigenic Specificity | USP22 (C-term) |
Clone | [1154CT13.1.3.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Purified His-tagged USP22 protein was used to produced this monoclonal antibody. Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression. |
Immunogen | n/a |
Other Names | [Ubiquitin carboxyl-terminal hydrolase 22; Deubiquitinating enzyme 22; Ubiquitin thioesterase 22; Ubiquitin-specific-processing protease 22; USP22; KIAA1063; USP3L] |
Gene, Accession # | [USP22], Gene ID: 23326, NCBI: NP_056091.1, UniProt: Q9UPT9 |
Catalog # | MBS9200278 |
Price | $165, $370 |
Order / More Info | USP22 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kikuno R., et al. DNA Res. 6:197-205(1999). Bechtel S., et al. BMC Genomics 8:399-399(2007). Lee H.-J., et al. Gene Expr. Patterns 6:277-284(2006). Zhao Y., et al. Mol. Cell 29:92-101(2008). Zhang X.-Y., et al. Mol. Cell 29:102-111(2008). |