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Antigenic Specificity | Scytovirin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | Scytonema varium |
Isotype | n/a |
Format | fluorescein (FITC) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Has strong anti-HIV activity against T-tropic strains of HIV-1 and weaker activity against M-tropic strains of HIV-1. Inhibits HIV-1 fusion and infection of CD4 LTR beta-gal cells in vitro. Inhibits fusion of HIV infected CEM-SS cells with uninfected CEM-SS cells, and fusion of HIV-1 Env expressing HL2/3 cells with CD4 LTR beta-gal cells. Binds to HIV gp120, HIV gp160 and to a lesser extent HIV gp41. Binding to HIV gp120 is glycosylation dependent. Binds with high specificity to the tetrasaccharide Man-alpha-1,2-Man-alpha-1,6-Man-alpha-1,6-Man and also binds the higher-order oligosaccharides oligomannose 8 and oligomannose 9. Does not bind to monosaccharides, complex or hybrid N-linked oligosaccharides or chitin. |
Immunogen | Immunogen: Recombinant Scytonema varium Scytovirin protein |
Other Names | [Scytovirin1] |
Gene, Accession # | NCBI: P86041.1, UniProt: P86041 |
Catalog # | MBS7000022 |
Price | $160, $235 |
Order / More Info | Scytovirin Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |