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Antigenic Specificity | CAMKK2 (C-term), 483-512 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CAMKK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-512 amino acids from the C-terminal region of human CAMKK2. CAMKK2 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. CAMKK2 appears to be involved in hippocampal activation of CREB1. |
Immunogen | n/a |
Other Names | [Calcium/calmodulin-dependent protein kinase kinase 2; CaM-KK 2; CaM-kinase kinase 2; CaMKK 2; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-KK beta; CaM-kinase kinase beta; CaMKK beta; CAMKK2; CAMKKB; KIAA0787] |
Gene, Accession # | [CAMKK2], Gene ID: 10645, NCBI: NP_001257414.1, UniProt: Q96RR4 |
Catalog # | MBS9202913 |
Price | $165, $370 |
Order / More Info | CAMKK2 (C-term), 483-512 Antibody from MYBIOSOURCE INC. |
Product Specific References | Hsu, L.S., et al., J. Biol. Chem. 276(33):31113-31123 (2001). Hsu, L.S., et al., J. Biomed. Sci. 5(2):141-149 (1998). Anderson, K.A., et al., J. Biol. Chem. 273(48):31880-31889 (1998). Ishikawa, Y., et al., FEBS Lett. 550 (1-3), 57-63 (2000). |