DNAJC10 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DNAJC10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: DNAJC10 antibody detects endogenous levels of DNAJC10. Function: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrect disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to en |
| Immunogen | Immunogen: A synthesized peptide derived from human DNAJC10. Subcellular Location: Secreted. Endoplasmic Reticulum Lumen. Tissue Specificity: By endoplasmic reticulum stress. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus Similarity: Pig (100%), Zebrafish (90%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (91%), Xenopus (82%) |
| Other Names | [DKFZp434J1813; DnaJ (Hsp40) homolog subfamily C member 10; DnaJ homolog subfamily C member 10; DNAJC 10; ER resident protein ERdj5; ERdj 5; ERdj5; J domain containing protein disulfide isomerase like protein; JPDI; Macrothioredoxin; MGC104194; MTHr] |
| Gene, Accession # | [DNAJC10], Gene ID: 54431, NCBI: NP_001258510.1, UniProt: Q8IXB1 |
| Catalog # | MBS9603497 |
| Price | $240, $280 |
| Order / More Info | DNAJC10 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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