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Antigenic Specificity | SOX2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SOX2 is a member of the SRY-related HMG-box (SOX) transcription factor family with a set of well-established and diverse roles in stem cell potency and maintenance, embryonic development and cancer. It regulates extensive and often divergent transcriptional networks across different cell types. SOX2 is best known as a core pluripotency factor, maintaining the undifferentiated phenotype of pluripotent stem cells, and is closely co-regulated alongside core pluripotency factors OCT4 and NANOG in undifferentiated ESCs (Embryonic Stem Cells), ECCs (Embryonal Carcinoma Cells) and iPSCs (Induced Pluripotent Stem Cells). Loss of SOX2 expression in these cell lines triggers their differentiation. More recently, SOX2 has been identified as a crucial |
Immunogen | Immunogen Information: A full length recombinant Sox2 protein was used as the immunogen for this antibody. |
Other Names | [SOX2; Transcription factor SOX-2; to SOX2; SOX2; SOX2], [SOX2; SOX2; ANOP3; MCOPS3] |
Gene, Accession # | [SOX2], Gene ID: 6657, NCBI: P48431.1, UniProt: P48431 |
Catalog # | MBS668786 |
Price | $140, $270 |
Order / More Info | SOX2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |