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Antigenic Specificity | TTL |
Clone | [654] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | Protein A purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tubulin-tyrosine ligase (TTL) is the enzyme responsible for the reversible addition of a tyrosine residue at the carboxyl end of alpha-tubulin. TTL forms stable complexes with tubulin and inhibit tubulin polymerization. TTL is frequently suppressed during tumor progression with resulting accumulation of detyrosinated alpha-tubulin in tumor cells. TTL suppression in human cancers is associated with increased tumor aggressiveness. |
Immunogen | Immunogen: Fusion protein of TTL |
Other Names | [2410003M22Rik; MGC46235; OTTHUMP00000161991; TTL; TTL; Tubulin tyrosine ligase; Tubulin--tyrosine ligase] |
Gene, Accession # | [TTL], Gene ID: 150465, NCBI: NP_714923.1, UniProt: Q8NG68 |
Catalog # | MBS2542244 |
Price | $220, $290, $435 |
Order / More Info | TTL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |