Edit |   |
---|---|
Antigenic Specificity | Human ACE-2 |
Clone | [11A31] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) - Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by the gene ACE belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. |
Immunogen | Antibody Generation: This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human ACE-2 recombinant protein (extracellular domain) |
Other Names | [ACE2; ACEH], [ACE2; ACE2; ACEH; ACEH] |
Gene, Accession # | [ACE-2], Gene ID: 59272, NCBI: NP_068576.1, UniProt: Q9BYF1 |
Catalog # | MBS690564 |
Price | $475 |
Order / More Info | Human ACE-2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |