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Antigenic Specificity | VPS16 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: VPS16 antibody detects endogenous levels of VPS16. Function: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to fu |
Immunogen | Immunogen: A synthesized peptide derived from human VPS16. Subcellular Location: Late Endosome Membrane. Lysosome Membrane. Cytoplasmic, peripheral membrane protein associated with late endosomes/lysosomes. Tissue Specificity: Ubiquitous. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken Similarity: Pig (80%), Zebrafish (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%) |
Other Names | [HGNC:14584; hVPS16; mVPS16; RP11 12M19.2; Vacuolar protein sorting 16 (yeast); Vacuolar protein sorting 16 (Yeast), isoform CRA_a; Vacuolar protein sorting 16; Vacuolar protein sorting 16 homolog (S. cerevisiae); vacuolar protein sorting associated protein 16 homolog; Vacuolar protein sorting protein 16; Vacuolar protein sorting-associated protein 16 homolog; VPS16; VPS16_HUMAN; VPS16A] |
Gene, Accession # | [VPS16], Gene ID: 64601, NCBI: NP_072097.2, UniProt: Q9H269 |
Catalog # | MBS9603470 |
Price | $240, $280 |
Order / More Info | VPS16 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |