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Antigenic Specificity | PIK3CB |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Involved in the activation of AKT1 upon stimulation by G-protein coupled receptors (GPCRs) ligands such as CXCL12, sphingosine 1-phosphate, and lysophosphatidic acid. May also act downstream receptor tyrosine kinases. Required in different signaling pathways for stable platelet adhesion a |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 771-1070 of human PIK3CB (NP 006210.1). |
Other Names | [PI3K; PIK3C1; P110BETA; PI3KBETA] |
Gene, Accession # | [PIK3CB], Gene ID: 5291, NCBI: NP_001242974.1, UniProt: P42338 |
Catalog # | MBS8544156 |
Price | $280 |
Order / More Info | PIK3CB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |