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Antigenic Specificity | MARCKS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The expression of a major cellular substrate for protein kinase C, the MARCKS protein, is regulated in a cell-, tissue-, and developmental stage-specific fashion; in addition, this expression can be stimulated acutely by various cytokines in certain cell types (1). MARCKS) binds calmodulin and is a predominant, specific substrate of PKC which is phosphorylated during macrophage and neutrophil activation, growth factor-dependent mitogenesis and neurosecretion; it is redistributed from plasma membrane to cytoplasm when phosphorylated and is involved in leukocyte motility. It has been reported that MARCKS is a filamentous (F) actin crosslinking protein, with activity that is inhibited by PKC-mediated phosphorylation and by binding to calcium-c |
Immunogen | Immunogen: A synthetic peptide of human MARCKS |
Other Names | [MACS; 80K-L; PKCSL; PRKCSL] |
Gene, Accession # | [MARCKS], Gene ID: 4082, NCBI: NP_002347.5, UniProt: P29966 |
Catalog # | MBS2547552 |
Price | $150, $225, $360 |
Order / More Info | MARCKS Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |