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Antigenic Specificity | ADAR1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ADAR1 protein. Catalyzes the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. This may affect gene expression and function in a number of ways that include mRNA translation by changing codons and hence the amino acid sequence of proteins; pre-mRNA splicing by altering splice site recognition sequences; RNA stability by changing sequences involved in nuclease recognition; genetic stability in the case of RNA virus genomes by changing sequences during viral RNA replication; and RNA structure-dependent activities such as microRNA production or targeting or protein-RNA interactions. Can edit both viral and cellular RNAs and can edit R |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human ADAR1. |
Other Names | [136 kDa double-stranded RNA binding protein; ADAR1; DRADA; DSH; DSRAD] |
Gene, Accession # | [ADAR1], Gene ID: 103, NCBI: NP_001020278.1, UniProt: P55265 |
Catalog # | MBS9409573 |
Price | $200, $255 |
Order / More Info | ADAR1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |