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Antigenic Specificity | Bak |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | ion exchange purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bak Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking |
Immunogen | Immunogen: Bak antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak. Buffer: Bak Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Bak; BAK; CDN1; BCL2L7; BAK-LIKE; BAK; Apoptosis regulator BAK; Bcl2-L-7; BCL2-antagonist/killer 1], [BAK1; BAK1; BAK; CDN1; BCL2L7; BAK-LIKE; BAK; BCL2L7; CDN1; Bcl2-L-7] |
Gene, Accession # | [BAK1], Gene ID: 578, NCBI: Q16611.1, UniProt: Q16611 |
Catalog # | MBS151433 |
Price | $375 |
Order / More Info | Bak Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |