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Antigenic Specificity | NPC/NPC1 |
Clone | [4H2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, k |
Format | Protein A purified |
Size | 0.05 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human NPC/NPC1. Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization ofcholesterol within the multivesicular environment of the late endosome(LE) to effect egress through the limiting bilayer of the LE. |
Immunogen | Immunogen: NPC1 (AAH63302, aa151-250 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Conjugation: Unconjugated |
Other Names | [Mouse (IgG1) to Human NPC/NPC1; NPC1; NPC; Niemann-Pick C1 protein; Niemann-Pick disease; type C1] |
Gene, Accession # | [NPC/NPC1], Gene ID: 4864 |
Catalog # | MBS2401388 |
Price | $605 |
Order / More Info | NPC/NPC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |