Ubiquitin D Antibody from MYBIOSOURCE INC.
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| Edit | |
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| Antigenic Specificity | Ubiquitin D |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.03 mg, 0.1 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into |
| Immunogen | Immunogen: A synthesized peptide derived from human Ubiquitin D. Subcellular Localization: Nucleus. Cytoplasm. Accumulates in aggresomes under proteasome inhibition conditions. Tissue Specificity: Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in the reticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland. |
| Other Names | [Ubiquitin D; Diubiquitin; Ubiquitin-like protein FAT10; UBD; FAT10], [UBD; UBD; FAT10; UBD-3; GABBR1; FAT10] |
| Gene, Accession # | [UBD], Gene ID: 10537, NCBI: NP_006389.2, UniProt: O15205 |
| Catalog # | MBS179779 |
| Price | $160, $340, $340 |
| Order / More Info | Ubiquitin D Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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