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Antigenic Specificity | STIM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin-embedded Section |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for Stromal interaction molecule 1(STIM1) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Stromal interaction molecule 1 is a protein that in humans is encoded by the STIM1 gene. STIM1 has a single transmembranedomain, and is localized to the endoplasmic reticulum, and to a lesser extent to the plasma membrane. This gene encodes a type 1 transmembrane protein that mediates Ca2+ influx after depletion of intracellular Ca2+ stores by gating of store-operated Ca2+ influx channels (SOCs). It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human STIM1(45-74aa AAEFCRIDKPLCHSEDEKLSFEAVRNIHKL), identical to the related mouse and rat sequences. |
Other Names | [Stromal interaction molecule 1; D11S4896E; GOK; OTTHUMP00000164512; OTTHUMP00000229140; OTTHUMP00000230742; stromal interaction molecule 1], [STIM1; STIM1; GOK; TAM; TAM1; IMD10; STRMK; D11S4896E;] |
Gene, Accession # | [STIM1], Gene ID: 6786, NCBI: NP_001264891.1, UniProt: Q13586 |
Catalog # | MBS178290 |
Price | $315 |
Order / More Info | STIM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Parker NJ, Begley CG, Smith PJ, Fox RM (Feb 1997). Molecular cloning of a novel human gene (D11S4896E) at chromosomal region 11p15.5. Genomics 37 (2): 253-6. 2. Soboloff, Jonathan; Rothberg, B. S.; Madesh, M.; Gill, D. L. (September 2012).STIM proteins: dynamic calcium signal transducers. Nat Rev Mol Cell Biol 13 (9): 549-65. 3. Williams RT, Manji SS, Parker NJ, Hancock MS, Van Stekelenburg L, Eid JP, Senior PV, Kazenwadel JS, Shandala T, Saint R, Smith PJ, Dziadek MA (Jul 2001).Identification and characterization of the STIM (stromal interaction molecule) gene family: coding for a novel class of transmembrane proteins. Biochem J 357 (Pt 3): 673-85. |