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Antigenic Specificity | MYD88 |
Clone | [AT22F11] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b kappa |
Format | Protein A purified |
Size | 0.05 mL |
Concentration | 1 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myeloid differentiation primary response gene 88 (MYD88) is adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. |
Immunogen | Immunogen: MYD88 antibody was raised in Mouse using recombinant human MYD88 (1-309aa) purified from E Coli as the immunogen |
Other Names | [Mouse MYD88; MYD88; MYD88; Myeloid differentiation primary response protein MyD88; MYD88D] |
Gene, Accession # | [MYD88], Gene ID: 35956, NCBI: NP_001286246.1 |
Catalog # | MBS5310102 |
Price | $245 |
Order / More Info | MYD88 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |