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Antigenic Specificity | KSHV ORF8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-KSHV ORF8 polyantibody recognizes specific in TPA-induced BCBL-1 cell lysate by the Western Blot. Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma- (2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells. |
Immunogen | Immunogen: Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8. |
Other Names | n/a |
Gene, Accession # | [KSHV ORF8] |
Catalog # | MBS418221 |
Price | $445 |
Order / More Info | KSHV ORF8 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. James J. Proc. Natl. Acad. Sci Vol. 1993, pp. 14862-14867. 2. Wang FZ. J Virol. 2003 Mar; 77 (5):3131-47 |