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Antigenic Specificity | TIM-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma. |
Immunogen | Immunogen: TIM-1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human TIM-1. Buffer: TIM-1 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TIM-1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1; Hepatitis A virus cellular receptor 1; Kidney injury molecule 1; HAVcr-1; hepatitis A virus cellular receptor 1], [HAVCR1; HAVCR1; TIM; KIM1; TIM1; HAVCR; KIM-1; TIM-1; TIMD1; TIMD-1; HAVCR-1; KIM1; TIM1; TIMD1; HAVcr-1; KIM-1; TIMD-1; TIM; TIM-1] |
Gene, Accession # | [HAVCR1], Gene ID: 26762, NCBI: NP_036338, UniProt: Q96D42 |
Catalog # | MBS150916 |
Price | $375 |
Order / More Info | TIM-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |