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Antigenic Specificity | Human Siglec-6 |
Clone | [42P40] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Siglecs are I-type (Ig-type) lectins belonging to the Ig superfamily. They are characterized by an N-terminal, Ig-like V-type domain that mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains (2 to 17), a single transmembrane region, and a cytoplasmic tail. The siglecs can be broadly classified into two subgroups: siglecs-1, -2, and -4, and a siglec-3/CD33-related subgroup (siglecs-3, and -5 through -13 in primates) defined by sequence similarity and clustered gene localization. They are widely expressed on hematopoietic cells, often in a cell-type-specific manner, and siglec-4/MAG is a myelin component in Schwann cells and oligodendrocytes. Their ligands, sialic acids, are negatively charged monosaccharides f |
Immunogen | n/a |
Other Names | [Sialic acid-binding Ig-like lectin 6; Sialic acid-binding Ig-like lectin 6; sialic acid-binding Ig-like lectin 6; sialic acid binding Ig like lectin 6; CD33 antigen-like 1; CDw327; Obesity-binding protein 1; OB-BP1; CD_antigen: CD327], [SIGLEC6; SIGLEC6; CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327; CD33L; CD33L1; OBBP1; Siglec-6; OB-BP1] |
Gene, Accession # | Gene ID: 946, NCBI: O43699.2, UniProt: O43699 |
Catalog # | MBS692373 |
Price | $490 |
Order / More Info | Human Siglec-6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |