MBP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMBP
Clone[4C6]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG
FormatProtein G purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionMonoclonal antibody to detect Myelin basic protein in human samples. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination; maybe as components of transcriptional complexes; and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a
Immunogenn/a
Other Names[Myelin A1 protein; Myelin membrane encephalitogenic protein], [Mbp; Mbp; jve; mld; shi; Hmbpr; C76307; R75289; golli-mbp; Shi; MBP]
Gene, Accession #[MBP], Gene ID: 17196, NCBI: NP_001020416.1, UniProt: P04370
Catalog #MBS845911
Price$345
Order / More InfoMBP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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