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Antigenic Specificity | MBP |
Clone | [4C6] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Monoclonal antibody to detect Myelin basic protein in human samples. The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination; maybe as components of transcriptional complexes; and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a |
Immunogen | n/a |
Other Names | [Myelin A1 protein; Myelin membrane encephalitogenic protein], [Mbp; Mbp; jve; mld; shi; Hmbpr; C76307; R75289; golli-mbp; Shi; MBP] |
Gene, Accession # | [MBP], Gene ID: 17196, NCBI: NP_001020416.1, UniProt: P04370 |
Catalog # | MBS845911 |
Price | $345 |
Order / More Info | MBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |