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Antigenic Specificity | HP1alpha, beta and gamma |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | Protein G purified |
Size | 0.025 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF), ChIP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal Antibody to detect HP1alpha, beta and gamma in human and mouse samples. Background: HP1 alpha, beta and gamma are components of heterochromatin. They recognize and bind histone H3 tails methylated at 'Lys-9', leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the inner nuclear membrane. |
Immunogen | Immunogen: Polyclonal antibody raised in rabbit against human HP1 beta (Heterochromatin protein 1 homolog beta), using the full length recombinant GST tagged protein. The antibody also recognizes the alpha and gamma isoforms. Positive Control: ChIP: NIH 3T3 cells, Western blot: HeLa cells, IF: HeLa cells. |
Other Names | [CBX5; 1; 3], [CBX3; HECH; HP1-GAMMA; HP1Hs-gamma] |
Gene, Accession # | Gene ID: 11335, NCBI: Q13185.4, UniProt: P45973 |
Catalog # | MBS840865 |
Price | $325 |
Order / More Info | HP1alpha, beta and gamma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |