Edit |   |
---|---|
Antigenic Specificity | NGAL |
Clone | [3C6-A7] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 3.96mg/ml |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids, steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase-associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron-containing siderophores. The presence of this protein in blood and urine is an early biomarker of acute kidney injury. This protein is thought to be be involved in multiple cellular processes, including maintenance of skin homeostasis, and suppression of invasiveness and metastasis. Mice lacking this gene are more susceptible to bacterial infection than wild type mice. |
Immunogen | Immunogen: Purified recombinant human NGAL protein expressed in E Coli. Sensitivity: This antibody detects endogenous levels of NGAL and does not cross-react with related proteins. Sequence Similarities: Belongs to the calycin superfamily. Lipocalin family. |
Other Names | [24p3; 25 kDa alpha 2 microglobulin related subunit of MMP9; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; Alpha 2 microglobulin related protein; HGNC:6526; HNL; Lcn 2; Lcn2; Lipocalin-2; Migration stimulating factor inhibitor; MSFI; Neutrophil gelatinase associated lipocalin; Neutrophil gelatinase associated lipocalin precursor; Neutrophil gelatinase-associated lipocalin; NGAL; NGAL_HUMAN; Oncogene 24p3; Oncogenic lipocalin 24p3; p25; Siderocalin; siderocalin LCN2; SV40 induced 24P3 protein; Uterocalin], [p25; 24p3; MSFI; NGAL; LCN2] |
Gene, Accession # | [NGAL], Gene ID: 3934, NCBI: NP_005555.2, UniProt: P80188 |
Catalog # | MBS477203 |
Price | $335 |
Order / More Info | NGAL Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |