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Antigenic Specificity | Human Protein S100-A8(S100A8) |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human. |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Specific for Human S100A8 denatured and native forms. S100A8 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis and adhesion. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Activates NADPH-oxidase by facilitating the enzyme complex assembly at the cell membrane, transferring arachidonic acid, an essential cofactor, t |
Immunogen | Immunogen: Recombinant Human S100A8 Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-53186 / sc-48352 / sc-53033 / sc-53184 / sc-33714 |
Other Names | [Calgranulin-A; Calprotectin L1L subunit; Cystic fibrosis antigen; CFAG; Leukocyte L1 complex light chain; Migration inhibitory factor-related protein 8; MRP-8; p8; S100 calcium-binding protein A8; Urinary stone protein band A], [S100A8; S100A8; P8; MIF; NIF; CAGA; CFAG; CGLA; L1Ag; MRP8; CP-10; MA387; 60B8AG; CAGA; CFAG; MRP8; CFAG; MRP-8; p8] |
Gene, Accession # | [S100A8], Gene ID: 6279, NCBI: NP_002955.2, UniProt: P05109 |
Catalog # | MBS1492041 |
Price | $185, $265 |
Order / More Info | Human Protein S100-A8(S100A8) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |