MEK Kinase-3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMEK Kinase-3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatimmunogen affinity purified
Size0.03 mL, 0.1 mL, 0.2 mL
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), ELISA (EIA)
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DescriptionSpecificity: MEK Kinase-3 Polyclonal Antibody detects endogenous levels of MEK Kinase-3 protein. MAP3K3 product is a 626-amino acid polypeptide that is 96% identical to mouse Mekk3. Its catalytic domain is closely related to those of several other kinases, including mouse Mekk2, tobacco NPK, and yeast Ste11. Northern blot analysis revealed a 4. -kb transcript that appears to be ubiquitously expressed. Mitogen-activated protein kinase kinase kinase 3 directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhanced transcription from a nuclear factor kappa-B (NFKB)
ImmunogenImmunogen: Synthesized peptide derived from the internal region of human MEK Kinase-3 at AA range: 70-150
Other Names[Rabbit MEK Kinase-3; MAP3K3; MAPKKK3; Mitogen-activated protein kinase kinase kinase 3; MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3]
Gene, Accession #[MEKK3], Gene ID: 4215, NCBI: NP_002392.2, UniProt: Q99759
Catalog #MBS9702463
Price$130, $220, $325
Order / More InfoMEK Kinase-3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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