TNF Receptor II Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TNF Receptor II |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total TNF Receptor II protein. Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.Smith C.A., Science 248:1019-1023(1990).Kohno T., Proc. Natl. Acad. Sci. U.S.A. 87:8331-8335(1990).Beltinger C.P., Genomics 35:94-100(1996). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from C-terminal of human TNF Receptor II. |
| Other Names | [Tumor necrosis factor receptor superfamily member 1B [Precursor]; Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; p75] |
| Gene, Accession # | [TNF], Gene ID: 7133, NCBI: NP_001057.1, UniProt: P20333 |
| Catalog # | MBS9414996 |
| Price | $200, $255 |
| Order / More Info | TNF Receptor II Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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