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Antigenic Specificity | Human Amyloid beta A4 protein A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G(o) alpha ATPase activity By similarity. Acts as a kinesin I membrane receptor, mediating the axonal transport of beta-secretase and presenilin 1. Involved in copper homeostasis/oxidative stress through copper ion reduction. In vitro, copper-metallated APP induces neuronal dea |
Immunogen | Immunogen: Peptide Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7496 / sc-7497 / sc-7498 / sc-5399 / sc-9129 |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS1488727 |
Price | $160, $235 |
Order / More Info | Human Amyloid beta A4 protein A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |