GAD1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-GAD1 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | GAD1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The enzyme glutamate decarboxylase (GAD) is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid (1). GAD1 (GAD67) and GAD2 (GAD65) are expressed in nervous and endocrine systems (2) and are thought to be involved in synaptic transmission (3) and insulin secretion (4), respectively. Autoantibodies against GAD2 may serve as markers for type I diabetes (5). Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2 (6). Mutations in the GAD1 gene can cause autosomal recessive spastic cerebral palsy, possibly attributable to altered glutamate/GABA ratios (7). |
| Immunogen | Immunogen: A synthetic peptide of human GAD1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [GAD; SCP; CPSQ1] |
| Gene, Accession # | [GAD1], Gene ID: 2571, NCBI: NP_000808.2, UniProt: Q99259 |
| Catalog # | MBS8502682 |
| Price | $310 |
| Order / More Info | GAD1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Kaufman, D.L. et al. (1991) J Neurochem 56, 720-3. 2. Feldblum, S. et al. (1993) J Neurosci Res 34, 689-706. 3. Gao, B. and Moore, R.Y. (1996) J Biol Rhythms 11, 172-9. 4. Rubi, B. et al. (2001) J Biol Chem 276, 36391-6. 5. Gilliam, L.K. et al. (2004) Clin Exp Immunol 138, 337-41. 6. Skorstad, G. et al. (2008) Eur J Neurol 15, 973-80. 7. Lynex, C.N. et al. (2004) BMC Neurol 4, 20. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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