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Antigenic Specificity | CHOLERA TOXIN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 1 mL |
Concentration | Approximate Protein concentration: 1.0 mg/ml |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti cholera toxin beta antibody recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. |
Immunogen | Immunogen: Purified Choleragenoid. Buffer Solution: Phosphate buffered saline Target Species: Bacterial |
Other Names | [cholera enterotoxin subunit B; Cholera enterotoxin subunit B; cholera enterotoxin subunit B; Cholera enterotoxin B chain; Cholera enterotoxin gamma chain; Choleragenoid], [VC1456; ctxB; toxB] |
Gene, Accession # | Gene ID: 2613962, NCBI: NP_231099.1, UniProt: P01556 |
Catalog # | MBS220376 |
Price | $485 |
Order / More Info | CHOLERA TOXIN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |