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Antigenic Specificity | DKC1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Isoform 1: Required for ribosome biogenesis and telomere maintenance. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine (' psi' ) residues, which may serve to stabilize the conformation of rRNAs. Also required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.Isoform 3: Promotes cell to cell and cell to substratum adhesion, increases the cell proliferation rate and leads to cytokeratin hyper-expression (wh |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human DKC1 (NP 001354.1). |
Other Names | [DKC; CBF5; DKCX; NAP57; NOLA4; XAP101] |
Gene, Accession # | [DKC1], Gene ID: 1736, NCBI: NP_001354.1, UniProt: O60832 |
Catalog # | MBS8548468 |
Price | $280 |
Order / More Info | DKC1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |