Edit |   |
---|---|
Antigenic Specificity | HERPUD1 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The accumulation of unfolded proteins in the endoplasmic reticulum (ER) triggers the ER stress response. This response includes the inhibition of translation to prevent further accumulation of unfolded proteins, the increased expression of proteins involved in polypeptide folding, known as the unfolded protein response (UPR), and the destruction of misfolded proteins by the ER-associated protein degradation (ERAD) system. This gene may play a role in both UPR and ERAD. Its expression is induced by UPR and it has an ER stress response element in its promoter region while the encoded protein has an N-terminal ubiquitin-like domain which may interact with the ERAD system. This protein has been shown to interact with presenilin proteins and to |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HERPUD1 |
Other Names | [homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform 2; Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein; homocysteine inducible ER protein with ubiquitin like domain 1; Methyl methanesulfonate (MMF)-inducible fragment protein 1] |
Gene, Accession # | [HERPUD1], Gene ID: 9709, NCBI: NP_001010989.1, UniProt: Q15011 |
Catalog # | MBS3221765 |
Price | $335 |
Order / More Info | HERPUD1 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |