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Antigenic Specificity | SCARB1/Sr Bi |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg, 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as high density lipoproteins (HDL) and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins (By similarity). Necessary for selective HDL-cholesterol uptake (PubMed: 26965621). Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate (By similarity). |
Immunogen | Immunogen: A synthesized peptide derived from human Scavenging Receptor SR-BI. Subcellular Localization: Cell membrane; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein. Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. Tissue Specificity: Widely expressed. |
Other Names | [Scavenger receptor class B member 1; SRB1; CD36 and LIMPII analogous 1; CLA-1; CD36 antigen-like 1; Collagen type I receptor; thrombospondin receptor-like 1; SR-BI; CD36; SCARB1; CD36L1; CLA1], [SCARB1; SCARB1; CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; CD36L1; CLA1; SRB1; CLA-1] |
Gene, Accession # | [SCARB1], Gene ID: 949, NCBI: NP_001076428.1, UniProt: Q8WTV0 |
Catalog # | MBS179552 |
Price | $160, $340, $340 |
Order / More Info | SCARB1/Sr Bi Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |